I used to rely heavily on the desktop app remembering where you left a certain playlist.
eg.: I'm at the bottom of Playlist A, I quickly go to Playlist B, then I click on Playlist A again and it opens at the bottom, where I last was positioned in this playlist.
With the new UI, every time you enter a playlist it puts you at the top. This is a major inconvenience for me, for sorting and playlist-making reasons.
EDIT: This seems to be the case in playlists, on artist pages and generally the whole app. A related problem is also that when you search a song, click it and then clear the filter, you jump back to the top instead of seeing the song you highlighted (thanks to @brian for pointing tis out.
This could be just a little hick-up since the UI changed, but I hope this is resolved soon!