If you are experiencing issues with sound quality, volume, distortion etc and you are running Android 5.x Lollipop please try disabling 'Nuplayer' from the developer settings. This is an experimental player Google introduced to Android and is known to cause some issues.
To disable open up the settings app from your app drawer. Scroll to the bottom and tap 'About'. Find the 'Build number' detail (possibly in 'Software information - More) and then tap on the build number 7 times until it flashes "You are now a developer".
Now go back to the settings screen and above where you tapped 'About' you should now see 'Developer Options'.
Tap this and scroll down until you see 'nuplayer', if it is checked uncheck it, go back to your homescreen and restart your devce. Hopefully the issues you had should be gone.
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After Spotify and Android update I have had the annoying problem of the music stopping after each track. The playlist show the next track and all, but it stops. So after trying you fix of disabling nuplayer it started doing something else. Now it plays tracks from Spotify quite well, but after 1 second playtime skipps tracks from my own library. All tracks imported from my library is MP3 and works fine on both Desktop and Mobile (if you could look beyond the 1 track playlist with the nuplayer activated). So it still dont work as it should.
Android version: 5.0.1
HTC Sense Version: 6.0
This has been reported several times and I have escalated it to the astaff so am hoping this gets fixed in the next update.